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Update from Syndel

* 4x1 Gallon Parasite-S (Formalin)* - FDA approved 37% formaldehyde in 4 * 1 gallon cases.                                                       

*5 Gallon 35% Perox-Aid®* - 35% hydrogen peroxide solution in 5 gallon carboys.


Both products are FDA approved for aquaculture!

For more information please contact:
(800) 283-5292 or



NEW Antibiotic Resistance Interactive Research Tool
U.S. Food and Drug Administration (FDA)

The U.S. Food and Drug Administration (FDA) has launched an interactive research tool called Resistome Tracker which is "... one of the first publicly available tools to provide visually informative displays of antibiotic resistance genes in bacteria. It is designed mainly for public health officials, academics and researchers who are using new genomics technologies to track and treat infectious diseases.

Resistome Tracker's interactive interface allows users to customize visualizations by antibiotic drug class, compare resistance genes across different sources, identify new resistance genes, and map selected resistance genes to geographic region ... The tool also provides alerts about new resistance traits as they emerge in a region or source to provide early warning on emergent trends ...

Currently, Resistome Tracker is focused on antibiotic resistance genes in Salmonella ... Future iterations of the tool will include data on other microorganisms such as E. coli and Campylobacter as well as additional gene categories such as serotype, sequence type and virulence genes ..."

Source: November 14, 2017 FDA CVM Update, titled "FDA Launches Resistome Tracker, an Interactive Research and Data Visualization Tool for Antibiotic Resistance Genes", posted at

Rest of report and links

GAO Report

Imported Seafood Safety - Preventing Unsafe Drug Residues

The US Government Accountability Office (GAO) has issued a report which found that "... FDA could strengthen its efforts to ensure the safety of imported seafood from unsafe drug residues by pursuing agreements with other countries requiring that they test seafood exported to the United States for unsafe drug residues ... FDA has used country agreements with respect to pathogen hazards in molluscan shellfish intended for export to the United States. According to FDA officials, it might be worthwhile for the agency to pursue agreements with some countries, but FDA would have to carefully consider a number of factors in determining which countries would be appropriate, which it has not yet done ..." 

The September 15, 2017 GAO Report is posted at


 from AADAP Updates

Catching Up With The AADAP Team

Looking for a little light reading and an opportunity to find out what the AADAP research team has been doing? Check out the recently published AADAP Drug Research Information Bulletins that will soon be posted on the AADAP website. And if you just can’t wait for them to get posted, contact Jim Bowker ( for a reprint.

Bowker, J.D., M. Bowman, N. Wandelear, J. T. Trushenski, and David Burbank. 2017. Effectiveness of AQUI-S®20E (10% eugenol) to Lightly Sedate Rainbow Trout, Cutthroat Trout, and Chinook Salmon. USFWS AADAP DRIB 52.

Owens, C., J. Bowker, and N. Wandelear. 2017. Use of AQUI-S®20E, Tricaine-STM, and AQUACALMTM to Sedate Rainbow Trout to Handleable. USFWS AADAP DRIB 53.

Bowker, J. N. Wandelear, and C. Silbernagel. 2017. Use of AQUI-S®20E to Sedate California Yellowtail and White Seabass to handleable. USFWS AADAP DRIB 54.

Wandelear, N, J. D. Bowker, and G. Eckerlin. 2017. Efficacy of Terramycin 200 for Fish (Oxytetracycline dihydrate) to Control Mortality in Tiger Musky Due to Columnaris. USFWS DRIB 55.


23rd Annual Aquaculture Drug Approval Coordination Workshop

The AADAP program hosted the 23rd Annual Aquaculture Drug Approval Coordination Workshop August 1-3, 2017, in Bozeman, Montana. There were 70 attendees, see photo, representing the U.S. Fish and Wildlife Service, National Oceanic and Atmospheric Administration, FDA Center for Veterinary Medicine, Department of Homeland Security, Association of Fish and Wildlife Agencies, state and tribal agencies, veterinarians, university researchers, private contracting laboratories and fish drug sponsors. The two days were packed full of presentations and activities.

Some of the workshop highlights included presentations on:

The increased AADAP budget and what that means to the future of fish drug approvals in the United States
♦ Research activities, particularly those involving work to support
             •New approvals for AQUI-S20E as a fish sedative
             •Expanding the current approval of TM200 for Fish
♦Research activities or status reports on
             •Idaho Dept. of Fish and Game’s YY Brook Trout Program and where this technology
              is heading
             •Use of GnRHIIa as a spawning aid
             •Use of Aquacalm (metomidate) to sedate rainbow trout to handleable
             •Use of Diquat to control mortality in walleye caused by columnaris disease
♦How to navigate the DHS Chemical Facility Anti-Terrorism Standards (CFATS) Chemical Security Assessment Tool (CSAT) Top-Screen website – necessary for those storing 35% Perox Aid on station.
♦The Veterinary Feed Direction rule change and interpretation of the Compliance Policy Guideline. It states that “In general, the agency [FDA] will not recommend or initiate enforcement action against the veterinarian, animal producer, feed mill, or other distributor when extralabel use" is authorized for a VFD medicated feed according to principles consistent with being a good veterinarian.

from AADAP Updates

FDA Clarifies Policy Guideline on Extralabel Use of Veterinary

Feed Directive Drugs

 One of the highlights of the 23rd Annual Aquaculture Drug Approval Coordination Workshop held August 1-3, 2017 in Bozeman, MT, was the series of presentations and panel discussion of Veterinary Feed Directives (VFDs) led by Dr. Mike Murphy (CVM Office of the Director, Science Policy Team). 

The VFD-themed session was organized because there has been considerable confusion over extra-label use of VFD drugs as described by the Compliance Policy Guideline (CPG) released in December 2016. Although such use is illegal, Dr. Murphy pointed to the sentence in the Guideline (CPG 615.115; page 5) that states "In general, the Agency [FDA] will not recommend or initiate enforcement action against the veterinarian, animal producer, feed mill, or other distributor when extralabel use is consistent with this document."

Compliance Policy Guideline 611.115 is for Minor Species only and can be viewed on this web page.

The document contains useful information and veterinarians will probably are probably very familiar with what is described in the (1) General Considerations and (2) Veterinarian Considerations sections. 

What may be of most interest in this document is the Veterinary Feed Directive (VFD) Medicated Feed subsection that covers what a veterinarian must do when authorizing the extralabel use of a VFD medicated feed for a minor species (i.e., fish). 

It should also be pointed out that CPG 615.115 can be rescinded. Therefore, there needs to be a concerted effort to ensure compliance with extralabel use of VFD medicated feeds. In addition, it would be well advised, to let the sponsor, AADAP, and CVM know when extralabel use occurs so we can more strategically coordinate research to expand the approved label accordingly. 

For more information on veterinarian responsibilities when authorizing extralabel use of a VFD medicated feed for fish visitFDA Revises CPG on Extralabel Use of Medicated Feeds for Minor Species.


USDA ARS News Release

A Big Step towards Reducing Strep in Farm-Raised Tilapia

Researchers with the USDA Agricultural Research Service (ARS) Aquatic Animal Health Research Unit in Auburn, Alabama and industry partners have developed tilapia that are resistant to both Streptococcus iniae and Streptococcus agalactiae, the "... main culprits [that cause] tilapia farmers lose about $1 billion annually due to streptococcosis ..."

The researchers showed that "... selective breeding for disease resistance is a promising alternative [to] vaccines and antibiotics ... They found that crosses between the best performing fish were more resistant to the bacteria than other tilapia ... This milestone research paves the way for developing more lines of tilapia with resistance to other pathogens ... Data shows that the improved tilapia lines will save an average-size farm nearly $635,000 a year annually ..."

USDA ARS News Release is posted at

After midterms last month, I had the opportunity to travel to Dallas, Texas, to attend the American Association of Zoo Veterinarians (AAZV) conference. The conference was held at the Embassy Suites Hotel and Convention Center in Frisco, Texas. The conference was also held concurrently with the American Association of Fish Veterinarians (AAFV), the Association of Exotic Mammal Veterinarians (AEMV), the Association of Reptile and Amphibian Veterinarians (ARAV), and the Association of Zoos and Aquariums Nutrition Scientific Advisory Group (NAG) conferences. Rest of story
Missed The 2017 AAFV Conference?
Register for the webcast!
And Remember - the 2017 AAFV Webcast is RACE Approved!

See our page link at the top on the conference




Radiographs courtesy of Dr. Shane Boylan, South Carolina Aquarium




Loan, Grant and Research Programs

 AQUAVET®Summer Research Fellow (one offered)
8 weeks following AQUAVET®I
Prerequisite is AQUAVET®I,
Laboratory Cornell University
Deadline Jan 15, 2018
More Info
Request for Applications: New Animal Drug Research
Grants to support the development of new animal drugs intended for minor species or minor uses in major species. Funding Opportunity Announcement #RFA-FD-15-004.
Final Application Date: January 12, 2018


Rqst for Applications HHS National Institutes of Health and USDA National Institute of Food and Agriculture: Dual Purpose Agricultural Farm Animal/Human Health Research Grant Funding
More information Deadline Aug 28, 2017/2018



Center for Fisheries, Aquaculture and Aquatic Science, SIU Carbondale
Job Description
Deadline: Nov 30, 2017 or until filled

UAPB Aquaculture /Fisheries Center
Research Assoc - Fish Pathology
Job Description - email Dr. Ramena
Deadline: Nov 16 or until filled

UAPB Aquaculture /Fisheries Center
Research Associate (Temporary) – Aquaculture/Seafood Economics and Marketing
Job Description
Deadline: Dec7 or until a suitable applicant is found



2018 Wildlife Exotic Animals Symposium (WEAS)
Hosted by Avian Exotics Medicine Club/UC Davis SVM
Feb 24-25, 2018
UC Davis
Davis, CA
More info

Hosted by Shark Reef Aquarium
March 2-4, 2018
Las Vegas, NV
More info will be posted later

JAN 15, 2018

AQUAVET®I - An Introduction to Aquatic Veterinary Medicine
May 27-June 23, 2018
Roger Williams Univ
Bristol, RI
More Info

AQUAVET®II - Comparative Pathology of Aquatic Animals
May 27-June 9, 2018
Roger Williams Univ
Bristol, RI
More Info

AQUAVET®III - Clinical Aspects of Captive Aquatic Animal Medicine
June 24 July 29, 2018
Week 1 & 2 - Georgia Aquarium, Atlanta GA
Week 3 - University of Georgia
Weeks 4 & 5 - Dolphinaris, Cancun, Mexico

More Info

59th Western Fish Disease Workshop
June 18-22, 2018
Bozeman, MT

More info pending

24th Annual Aquaculture Drug Approval Coordination Workshop
June 18-22, 2018
Bozeman, MT
More info pending

2018 ISAAH
September 2-6, 2018
Charolettetown, PEI, Canada